UDP-GlcNAc 2-epimerase/ManNAc 6-kinase, GNE, is a bi-functional enzyme that plays a key role in sialic acid biosynthesis.Mutations of the GNE protein cause sialurea or autosomal recessive inclusion body myopathy/Nonaka myopathy.GNE is the only human protein that contains a kinase domain belonging to the ROK (repressor, ORF, kinase) family.We solved
Wireless Sensor Networks (WSNs) offer a powerful technology for sensing and transmitting data across vast geographical regions.However, limitations inherent to WSNs, such as low-power sensor units, communication constraints, and limited processing capabilities, can significantly impact their lifespan.To address these limitations and enhance the ene
We attempt to provide g35 coupe fender a mesoscopic treatment of the origin of black hole entropy in (3 + 1)-dimensional spacetimes.We ascribe this entropy to the non-trivial topology of the space-like sections Σ of the horizon.This is not forbidden by topological censorship, since all the known energy inequalities needed to prove the spherica
It here is estimated that 1 in 10 hospital inpatients in Scotland have experienced a medication error.In our unit, an audit in 2019 identified documentation of as-required prescriptions on drug Kardexes as an important target for improvement.This project aimed to reduce the percentage of these errors to <5% in the ward in 6 months.Weekly point p
The effects of wood species and panel connections on the vibration and heavy-weight impact sound insulation performance of cross-laminated timber (CLT) slabs were investigated.CLT panels (5-ply, 150 mm thick, 1 m wide, and 4.2 m long) made of larch (Larix kaempferi) and pine (Pinus densiflora) were manufactured with 30 mm thick laminae, considering